Valacyclovir, delivered to your door
Prescription antiviral medication for genital herpes outbreaks and cold sores treatment.
Start nowAbout valacyclovir
Valacyclovir is a prescription antiviral medication commonly known by its brand name Valtrex. It belongs to a class of medications called nucleoside analogues and works by interfering with the herpes simplex virus's ability to replicate. This stops the virus from spreading, reducing the severity and duration of outbreaks.
HSV-1 and HSV-2 affect millions of Americans. Valacyclovir is a safe, effective treatment that can manage outbreaks and reduce transmission risk. It's more common than you think, and treatment is just a few clicks away.
Start nowHow valacyclovir works
Daily use (suppressive therapy)
Taken daily, valacyclovir can reduce how often you experience herpes outbreaks. Studies have shown that suppressive therapy reduces the risk of giving herpes to a partner by about 50%. Daily treatment is recommended for people with frequent outbreaks (typically six or more per year) or those who want to minimize transmission risk to a sexual partner.
At first signs (episodic therapy)
When taken at the first signs of an outbreak — ideally within 24 to 48 hours of symptom onset — valacyclovir can shorten the duration of a herpes outbreak and help it heal faster. This approach is ideal for people who experience occasional outbreaks and prefer to treat them as needed rather than taking daily medication.
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Frequently asked questions about valacyclovir
Valacyclovir is a prescription antiviral medication used to treat and prevent outbreaks of herpes viruses. It is the generic version of Valtrex and is used to treat conditions including genital herpes outbreaks and cold sores. Valacyclovir works by stopping the herpes virus from multiplying in the body.
Valacyclovir is converted into acyclovir in the body. Acyclovir works by interfering with the herpes virus's ability to replicate, which stops the virus from spreading and allows your immune system to fight the infection more effectively. This reduces the severity and duration of outbreaks.
Most people notice improvement within 2 to 3 days of starting valacyclovir treatment. When taken at the first signs of an outbreak, valacyclovir can significantly shorten the duration of symptoms and speed up healing. For suppressive therapy (daily use), benefits may become more noticeable over the following weeks.
Common side effects include headache, nausea, vomiting, dizziness, and abdominal pain. Serious side effects are rare but can include kidney problems and changes in blood cell counts. Contact your provider if you experience unusual fatigue, decreased urination, or signs of an allergic reaction.
Valacyclovir is available in 500 mg and 1 g tablets. The appropriate dose depends on the condition being treated and whether you are using episodic or suppressive therapy. Your provider will recommend the right dose for you.
Valacyclovir and acyclovir both treat herpes viruses, but valacyclovir has better oral bioavailability. This means the body absorbs valacyclovir more efficiently, allowing for fewer daily doses compared to acyclovir while achieving the same therapeutic effect.
What is valacyclovir?
Valacyclovir is a prescription antiviral medication approved for the treatment of genital herpes and cold sores (oral herpes). It is the generic equivalent of Valtrex and is taken orally in tablet form.
Who should not take valacyclovir?
Do not take valacyclovir if you are allergic to valacyclovir, acyclovir, or any of the inactive ingredients. Inform your provider if you have kidney disease, a weakened immune system (e.g., from HIV/AIDS or organ transplant), or are taking medications that affect the kidneys.
Warnings and precautions
Valacyclovir may cause kidney problems, especially in older adults or those with existing kidney disease. Drink adequate fluids while taking this medication. In rare cases, valacyclovir can cause thrombotic thrombocytopenic purpura (TTP) or hemolytic uremic syndrome (HUS), which are serious blood disorders. Seek immediate medical attention if you experience unusual bruising, bleeding, fatigue, dark urine, or reduced urination.
Drug interactions
Tell your provider about all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Valacyclovir may interact with drugs that affect kidney function. Your provider will review your medications and adjust dosages as needed.
Pregnancy and breastfeeding
Tell your provider if you are pregnant, planning to become pregnant, or breastfeeding. The use of valacyclovir during pregnancy and breastfeeding should be discussed with your healthcare provider to weigh the potential benefits and risks.
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